Heat vs. Cold Therapy: Which is Best for Musculoskeletal Injuries
When treating musculoskeletal injuries, chiropractors often face the key question of when to use heat vs ice therapy. Understanding the benefits of ice and heat therapy can significantly impact a patient's healing journey. This blog breaks down evidence-based guidance on heat and ice therapy, highlighting when each can be most beneficial.
When to Use Ice vs Heat for Musculoskeletal Injuries
Heat and cold therapy both play valuable roles in managing pain and promoting healing. However, their mechanisms and effects differ. Selecting the right modality depends on understanding these mechanisms and the specific injury or condition.
Mechanism of Action and Benefits of Cold Therapy
Cold therapy, or cryotherapy, is commonly used immediately following an acute injury to reduce inflammation and limit tissue damage. (1) This method is particularly beneficial for soft-tissue injuries such as sprains, strains, and swelling, as it decreases blood flow, lowers metabolic demand, and reduces tissue temperature, all contributing to its effectiveness. (2) Ice therapy benefits are primarily achieved through the following physiological mechanisms:
Pain Relief: Ice numbs the affected area, temporarily suppressing nerve activity (NCV) and muscle spasms. (1,3)
Reduced Swelling: Ice minimizes fluid buildup in the injured area through vasoconstriction of arterioles and capillaries, effectively controlling swelling. (1,2)
Reduced Immune Cell Activity: Cold therapy decreases the presence of leukocytes, granulocytes, and macrophages—key immune cells involved in inflammation. (2)
Limiting Secondary Injury?: Many clinicians and some researchers believe that ice therapy can limit subsequent tissue damage and potentially support muscle regeneration by reducing the immediate pro-inflammatory response. This belief is primarily based on animal studies, which suggest that early application of ice can help control inflammation and minimize further injury within the first 6-12 hours. (2,3) However, a critical review published in the October 2024 British Medical Journal found no conclusive evidence from human studies that cryotherapy effectively limits secondary injury or promotes tissue regeneration. (4)
When to Use Ice Therapy
Acute MSK Injuries- i.e., sprains, strains, contusions, etc. Cold therapy has proven to be most beneficial for controlling excessive swelling within the first 6-12 hours post-injury. (1-3)
Migraine Headaches: Using ice for migraines can provide relief. (5-7) Applications include cold-gel headbands or caps placed on the forehead and wraps applied to the neck to target the carotid arteries. (7)
Acute Rheumatologic Flare-Ups: While there is no research consensus, ice therapy is generally considered beneficial for reducing inflammation in acute rheumatologic flare-ups, particularly in cases of gout. (8-9,38)
Post-Knee Arthroplasty: Studies indicate that cold compression therapy after knee replacement surgery can improve outcomes, such as better pain relief, compared to other treatment methods. (10,11)
Cooling Controversy: Rethinking Ice for Injury Recovery
The RICE protocol (Rest, Ice, Compression, Elevation), introduced by Dr. Gabe Mirkin in 1978 in The Sports Medicine Book (12), was long considered the gold standard for treating acute injuries. However, Dr. Mirkin has since revised his stance, suggesting that ice should be used cautiously post-injury. (13) Emerging data indicates that while ice therapy can reduce pain and control swelling in the immediate aftermath of an injury, prolonged cooling (beyond 6-12 hours) may actually hinder recovery by delaying tissue repair and increasing scar tissue formation. (3,4,14-17)
Rather than aiming to eliminate inflammation, current recommendations focus on regulating and optimizing the inflammatory response to support recovery. Recent evidence has led practitioners to shift from RICE to the PEACE & LOVE approach, which emphasizes early protection, elevation, avoiding antiinflammatories, compression, and education, followed by (controlled) loading, optimism, vascularization, and exercises. (2)
ChiroUp subscribers can download our newest infographic in the Forms Library by searching “PEACE and LOVE”.
The new cold, hard truth about ice therapy vs heat therapy: While ice likely remains helpful in the first 6-12 hours post-injury to alleviate acute symptoms, it may act as a barrier to healing if used too long, potentially leading to tissue damage and even nerve injury. (2,4) Consequently, ice is now considered best for short-term pain management rather than a primary strategy for ongoing recovery from musculoskeletal injuries.
Practical Application of Ice Therapy
Types of cold therapy: Ice pack therapy, migraine ice cap, bagged ice, compressive cryotherapy devices, immersion ice bath therapy, or whole-body cryotherapy chambers. (11)
The optimal temperature of ice therapy: Undefined and dependant on the amount of internal and external insulation. Somewhere between cool water and nearly 0 degrees Celsius for a chemical instant ice pack (which carries a frostbite risk).
How long to apply ice therapy: 10-20 minutes. (2,18) When using an ice pack, patients may progressively feel cold, followed by burning, aching, and finally numbness (CBAN). Remove the ice pack if numbness occurs.
Contraindications for Ice Therapy: Ice therapy should be avoided in cases of impaired circulation, Raynaud’s disease, cryoglobulinemia, hemoglobinuria, peripheral vascular disease, hypersensitivity to cold, cold urticaria, Complex Regional Pain Syndrome (CRPS), or skin anesthesia. It is also contraindicated over regenerating nerves, open wounds, or burns, as it can worsen tissue damage or lead to hypothermia. Whole-body immersion and cryotherapy chambers should be used with caution to avoid potential side effects like hypotension, tachycardia, and syncope. Proper screening and precautions are essential, especially with prolonged exposure or specific applications like ice massage or cold packs. (8,19-21)
Mechanism of Action and Benefits of Heat Therapy
Heat therapy is particularly useful in managing chronic or subacute musculoskeletal pain. It increases blood flow, improving tissue elasticity, muscle flexibility, and oxygenation. Heat also activates thermoreceptors, blocking pain signals to the brain and providing relief for conditions like low back pain. (1,22) Heat therapy benefits are primarily achieved through the following physiological mechanisms:
Pain Relief: Heat therapy activates temperature-sensitive nerve endings (thermoreceptors), which help block pain signals by inhibiting nociceptive processing. Additionally, the pressure concurrently used in some heat applications can stimulate proprioceptors, further reducing pain signals. (22)
Increased Blood Flow and Metabolism: Heat application boosts blood flow and metabolic activity, delivering more oxygen and nutrients to tissues. This increase in circulation supports muscle function and may enhance strength and mobility. (1,22)
Enhanced Muscle Flexibility and Tissue Elasticity: Heat improves muscle flexibility and connective tissue elasticity, aiding mobility and reducing stiffness. (1,22)
Improved Muscle Strength and Activation?: Heat therapy increases blood flow, enhancing the supply of oxygen and nutrients to muscles. This boost in metabolic activity supports greater muscle fiber activation, potentially improving muscle strength and function. (22)
When to Use Heat Therapy
Lower Back Pain: Heat therapy is recommended for managing non-specific low back pain in acute, sub-acute, and chronic phases. Clinical practice guidelines from the Annals of Internal Medicine support heat therapy for reducing pain and improving function across these stages. (26) Studies indicate that heat therapy provides short-term relief from pain and disability. (22-26) and that combining heat therapy with other treatments may even improve muscle strength in chronic lower back pain. (27)
Non-acute Mechanical Pain: Heat therapy is beneficial for managing sub-acute and chronic mechanical nociceptive pain conditions, including tendinosis and osteoarthritis. It is also recommended for strains and sprains during the sub-acute and chronic rehabilitation phases once the acute phase has passed.
Pre-Workout: Applying heat before exercise can enhance physical function, range of motion, and flexibility, reducing the risk of muscle strain or stiffness. Research has shown that using low-level heat therapy a few hours before intense exercise provides pain relief and improves movement, helping to prevent muscular damage during activity. (28,29)
Delayed Onset Muscle Soreness (DOMS): Evidence is mixed on whether ice or heat is best for DOMS relief. Some studies recommend starting with ice and then switching to heat. (30) A review of over 50 studies suggests that heat provides the most effective pain relief in the first 24 hours post-exercise, with cryotherapy being more effective after 48 hours. (31) Some research finds heat more beneficial overall than cold therapy for DOMS (1); other studies suggest both methods are similarly effective. (32)
Dysmenorrhea: Most experts (78%) agree that heat therapy may be used to relieve pain associated with dysmenorrhea. (22)
Practical Application of Heat Therapy
Types of heat therapy: Moist heat therapy (Hydrocollator®, etc), heating pads, heat wraps, immersion/ hot tub
Optimal Temperature for Heat Therapy: Most experts agree that 40°C (104°F) is an effective and safe temperature for superficial heat therapy. (22,25,28,33-35) Studies have shown that increasing tissue temperature to 38°C, 40°C, and 42°C in the trapezius muscle increases local blood flow by 27%, 77%, and 144%, respectively. (36)
How long to apply heat therapy: The time needed to reach these temperatures varies by body composition; for example, 2 cm of subcutaneous fat may take up to 30 minutes to achieve the desired therapeutic effect. (22)
Contraindications for Heat Therapy: Heat should be avoided for acute pain following trauma as it can increase inflammation in acute inflammatory conditions. (37) Heat therapy also requires intact skin and should be used cautiously or avoided entirely in individuals with active autoimmune conditions, skin disorders (i.e., herpes zoster), infections, malignancies, inflammatory diseases including inflammatory joint pain, pregnancy, or neurological conditions that may alter peripheral sensitivity, such as multiple sclerosis, ALS, spinal injuries, and diabetes. Additionally, heat therapy is not recommended during pregnancy. (22,37)
Key Takeaways for Clinical Practice
By understanding the principles and consulting current research, chiropractors can offer patients an evidence-based approach to using heat and ice therapy. Such strategies can not only enhance patient comfort but also promote long-term healing.
ChiroUp subscribers can also download our other latest infographic in the Forms Library by searching “Ice Therapy vs. Heat Therapy”. This visual guide helps patients understand which therapy to use, making it easier to follow your recommendations and get the most out of their recovery.
Confident Care Starts with Updated Knowledge
Deciding between heat and ice therapy is just one example of evidence-based practice in action. With ChiroUp’s 180+ updated protocols, you’re not just keeping up with research—you’re using it to give every patient the best possible care.
-
1. Malanga GA, Yan N, Stark J. Mechanisms and efficacy of heat and cold therapies for musculoskeletal injury. Postgraduate medicine. 2015 Jan 2;127(1):57-65. Link
2. Wang ZR, Ni GX. Is it time to put traditional cold therapy in rehabilitation of soft-tissue injuries out to pasture?. World journal of clinical cases. 2021 Jun 6;9(17):4116. Link
3. Kwiecien SY. Is it the End of the Ice Age?. International Journal of Sports Physical Therapy. 2023;18(3):547. Link
4. Racinais S, Dablainville V, Rousse Y, Ihsan M, Grant ME, Schobersberger W, Budgett R, Engebretsen L. Cryotherapy for treating soft tissue injuries in sport medicine: a critical review. British Journal of Sports Medicine. 2024 Oct 1;58(20):1215-23. Link
5. Hsu YY, Chen CJ, Wu SH, Chen KH. Cold intervention for relieving migraine symptoms: A systematic review and meta-analysis. J Clin Nurs. 2023 Jun;32(11-12):2455-2465. doi: 10.1111/jocn.16368. Epub 2022 May 20. PMID: 35596276. Link
6. Ucler S, Coskun O, Inan LE, Kanatli Y. Cold Therapy in Migraine Patients: Open‐label, Non‐controlled, Pilot Study. Evidence‐Based Complementary and Alternative Medicine. 2006;3(4):489-93. Link
7. Sprouse-Blum AS, Gabriel AK, Brown JP, Yee MH. Randomized controlled trial: targeted neck cooling in the treatment of the migraine patient. Hawai'i Journal of Medicine & Public Health. 2013 Jul;72(7):237. Link
8. Garcia C, Karri J, Zacharias NA, Abd-Elsayed A. Use of cryotherapy for managing chronic pain: an evidence-based narrative. Pain and therapy. 2021 Jun;10:81-100. Link
9. Schlesinger N, Detry MA, Holland BK, Baker DG, Beutler AM, Rull M, Hoffman BI, Schumacher HR. Local ice therapy during bouts of acute gouty arthritis. The Journal of Rheumatology. 2002 Feb 1;29(2):331-4. Link
10. Block JE. Cold and compression in the management of musculoskeletal injuries and orthopedic operative procedures: a narrative review. Open access journal of sports medicine. 2010 Jul 7:105-13. Link
11. Kunkle BF, Kothandaraman V, Goodloe JB, Curry EJ, Friedman RJ, Li X, Eichinger JK. Orthopaedic application of cryotherapy: a comprehensive review of the history, basic science, methods, and clinical effectiveness. JBJS reviews. 2021 Jan 1;9(1):e20. Link
12. Mirkin G, Hoffman M. The Sports Medicine Book. Little, Brown & Company (Canada) Limited. 1978
13. Mirkin, G. (2015, September). Why ice delays recovery. Dr Gabe Mirkin on Health. Retrieved on 11/12/2024 from Link
14. Takagi R, Fujita N, Arakawa T, Kawada S, Ishii N, Miki A. Influence of icing on muscle regeneration after crush injury to skeletal muscles in rats. Journal of applied physiology. 2011 Feb;110(2):382-8. Link
15. Singh DP, Barani Lonbani Z, Woodruff MA, Parker TJ, Steck R, Peake JM. Effects of topical icing on inflammation, angiogenesis, revascularization, and myofiber regeneration in skeletal muscle following contusion injury. Frontiers in physiology. 2017 Mar 7;8:93. Link
16. Miyakawa M, Kawashima M, Haba D, Sugiyama M, Taniguchi K, Arakawa T. Inhibition of the migration of MCP-1 positive cells by icing applied soon after crush injury to rat skeletal muscle. Acta Histochemica. 2020 Apr 1;122(3):151511. Link
17: Horschig A, Sonthana K, Williams B, Horgan M, Starrett K. The Efficacy Of Icing For Injuries And Recovery - A Clinical Commentary. JCC. 2024;7(1):96-101. Link
18. Kuo CC, Lin CC, Lee WJ, Huang WT. Comparing the antiswelling and analgesic effects of three different ice pack therapy durations: a randomized controlled trial on cases with soft tissue injuries. Journal of Nursing Research. 2013 Sep 1;21(3):186-93. Link
19. Chanliongo PM. Cold (cryo) therapy. In: Lennard TA, Walkowski S, Singla AK, Vivian DG, editors. Pain procedures in clinical practice. Philadelphia: Elsevier; 2011. pp. 555–558.
20. Behrens BJ, Beinert H. Physical agents: theory and practice. 3. Philadelphia: F. A. Davis Company; 2014.
21. Benny B, Grabois M, Chan K. Physical medicine techniques in pain management. In: Benzon HT, Rathmell JP, Wu CL, Turk DC, Argoff CE, Hurley RW, editors. Practical management of pain. Elsevier: Philadelphia; 2014. pp. 629–641.
22. Lubrano E, Mazas PF, Freiwald J, Krüger K, Grattagliano I, Mur E, Silva RQ, Maruri GR, de Medeiros LS. An international multidisciplinary delphi-based consensus on heat therapy in musculoskeletal pain. Pain and therapy. 2023 Feb;12(1):93-110. Link
23. Freiwald J, Magni A, Fanlo-Mazas P, Paulino E, Sequeira de Medeiros L, Moretti B, Schleip R, Solarino G. A role for superficial heat therapy in the management of non-specific, mild-to-moderate low back pain in current clinical practice: A narrative review. Life. 2021 Aug 2;11(8):780. Link
24. Gianola S, Castellini G, Andreano A, Corbetta D, Frigerio P, Pecoraro V, Redaelli V, Tettamanti A, Turolla A, Moja L, Valsecchi MG. Effectiveness of treatments for acute and sub-acute mechanical non-specific low back pain: protocol for a systematic review and network meta-analysis. Systematic reviews. 2019 Dec;8:1-8. Link
25. Gianola S, Bargeri S, Del Castillo G, Corbetta D, Turolla A, Andreano A, Moja L, Castellini G. Effectiveness of treatments for acute and subacute mechanical non-specific low back pain: a systematic review with network meta-analysis. British journal of sports medicine. 2022 Jan 1;56(1):41-50. Link
26. Qaseem A, Wilt TJ, McLean RM, Forciea MA, Clinical Guidelines Committee of the American College of Physicians*. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians. Annals of internal medicine. 2017 Apr 4;166(7):514-30. Link
27. Freiwald J, Hoppe MW, Beermann W, Krajewski J, Baumgart C. Effects of supplemental heat therapy in multimodal treated chronic low back pain patients on strength and flexibility. Clinical Biomechanics. 2018 Aug 1;57:107-13. Link
28. Mayer JM, Mooney V, Matheson LN, Erasala GN, Verna JL, Udermann BE, Leggett S. Continuous low-level heat wrap therapy for the prevention and early phase treatment of delayed-onset muscle soreness of the low back: a randomized controlled trial. Archives of physical medicine and rehabilitation. 2006 Oct 1;87(10):1310-7. Link
29. Petrofsky JS, Khowailed IA, Lee H, Berk L, Bains GS, Akerkar S, Shah J, Al-Dabbak F, Laymon MS. Cold vs. heat after exercise—is there a clear winner for muscle soreness. The Journal of Strength & Conditioning Research. 2015 Nov 1;29(11):3245-52. Link
30. Hotfiel T, Carl HD, Swoboda B, Heinrich M, Heiß R, Grim C, Engelhardt M. Current conservative treatment and management strategies of skeletal muscle injuries. Zeitschrift fur Orthopadie und Unfallchirurgie. 2016 Jun 28;154(3):245-53. Link
31. Yutan WA, Hongmei LU, Sijun LI, Zhang Y, Fanghong YA, Huang Y, Xiaoli CH, Ailing YA, Lin HA, Yuxia MA. Effect of cold and heat therapies on pain relief in patients with delayed onset muscle soreness: A network meta-analysis. Journal of rehabilitation medicine. 2022;54. Link
32. Wang Y, Li S, Zhang Y, Chen Y, Yan F, Han L, Ma Y. Heat and cold therapy reduce pain in patients with delayed onset muscle soreness: A systematic review and meta-analysis of 32 randomized controlled trials. Physical Therapy in Sport. 2021 Mar 1;48:177-87. Link
33. Petrofsky JS, Laymon M, Alshammari F, Khowailed IA, Lee H. Use of low level of continuous heat and Ibuprofen as an adjunct to physical therapy improves pain relief, range of motion and the compliance for home exercise in patients with nonspecific neck pain: a randomized controlled trial. Journal of back and musculoskeletal rehabilitation. 2017 Jan 1;30(4):889-96. Link
34.Lewis SE, Holmes PS, Woby SR, Hindle J, Fowler NE. Short-term effect of superficial heat treatment on paraspinal muscle activity, stature recovery, and psychological factors in patients with chronic low back pain. Archives of physical medicine and rehabilitation. 2012 Feb 1;93(2):367-72. Link
35. Mayer JM, Ralph L, Look M, Erasala GN, Verna JL, Matheson LN, Mooney V. Treating acute low back pain with continuous low-level heat wrap therapy and/or exercise: a randomized controlled trial. The Spine Journal. 2005 Jul 1;5(4):395-403. Link
36. Erasala GN, Rubin JM, Tuthill TA, Fowlkes JB, de Drue SE, Hengehold DA, Weingand KJ. The effect of topical heat treatment on trapezius muscle blood flow using power Doppler ultrasound. Physical Therapy. 2001;81(5):A5
37. Nadler SF, Weingand K, Kruse RJ. The physiologic basis and clinical applications of cryotherapy and thermotherapy for the pain practitioner. Pain physician. 2004;7(3):395. Link
38. Schlesinger N. Response to application of ice may help differentiate between gouty arthritis and other inflammatory arthritides. JCR: Journal of Clinical Rheumatology. 2006 Dec 1;12(6):275-6. Link